Vention Medical

Vention Medical is proud to be a true innovator in the field of medical device and component design, development and manufacture. Together with our partners, we work to achieve the complex components, devices and solutions of the future — the ones that will forever impact the medical industry, and the lives of the people they touch.

We do this by continually progressing the way we think and work — reviewing and examining existing products and processes, and researching and developing new technologies, solutions and methodologies. This constant evolution serves to provide us with the innovative approach that helps drive our industry — and our customers’ businesses — forward in every way.

As a result of our dedication to innovation, we have achieved a broad range of advanced patents and processes, including being the manufacturer of the world’s thinnest, strongest and smallest heat shrink tubing since 1989. Members of our team are also named on over 70 patents — exceptional products invented and developed here at Vention Medical, but now residing in the ownership of valued customers and partners worldwide.

Published Patents Owned by Mark A. Saab or Advanced Polymers include

• 5,246,421: Method of Treating Obstructed Regions of Bodily
  An adjustable-length balloon dilatation catheter apparatus and a method for using the same are disclosed wherein an adjustable sheath is externally manipulated to partially surround and contain the dilatation balloon segment of the catheter while the catheter and balloon segment are in situ during a treatment procedure. By sliding the sheath forward or backward to expose a predetermined length of the balloon segment prior to inflating the balloon, the catheter apparatus of this invention is useful in medical procedures requiring balloons of varying lengths.
• 5,264,260: Dilatation Balloon Fabricated from Low Molecular Weight Polymers
  A low molecular weight, flexible, biaxially oriented, dilatation catheter balloon comprising oriented polyethylene terephthalate, and having a calculated radial tensile strength of greater than about 25,000 psi
• 5,337,734: Disposable Sheath with Optically Transparent Window Formed Continuously Integral Therewith
  Sterile disposable coverings for endoscopes and similar optical medical instruments are disclosed together with a method for preparing such coverings. By forming a heated polymeric film with a mandrel of appropriate shape and dimensions, relatively long-length, very small diameter, closely-fitting, thin-walled sleeves are produced, each having a thin, substantially inelastic, optically transparent window formed continuously integral with the sleeve at or proximate to the closed, distal end of the sleeve.
• 5,342,301: Multi-Lumen Balloons and Catheters Made Therewith
  Multi-lumen balloons for use as or in conjunction with balloon dilation catheters, and methods for making such balloons, are disclosed.
• 5,411,477: High-Strength, Thin-Walled Single Piece Catheters
  An integral, single-piece, high-strength, thin-walled, inflatable catheter is disclosed. The catheter has one end partially or entirely closed, and is at least uniaxially oriented along its entire length. The methods and apparatus for making the catheter is also disclosed. The catheters of this invention have a calculated radial tensile strength of about 10,000 psi or greater at every point along the catheter.
• 5,443,781: Method of Preparing Disposable Sheath with Optically Transparent Window Formed Continuously Integral Therewith
  Sterile disposable coverings for endoscopes and similar optical medical instruments are disclosed together with a method for preparing such coverings. By forming a heated polymeric film with a mandrel of appropriate shape and dimensions, relatively long-length, very small diameter, closely-fitting, thin-walled sleeves are produced, each having a thin, substantially inelastic, optically transparent window formed continuously integral with the sleeve at or proximate to the closed, distal end of the sleeve.
• 5,499,973: Variable Stiffness Balloon Dilatation Catheters
  A variable stiffness balloon dilatation catheter is disclosed in which one or more polymeric sleeves are heat-shrunk around portions of an inner tubular element so as to form stiffening bands that provide variable stiffness longitudinally along the catheter.
• 5,569,195: Medical Balloon and Method of Making Same
  Multi-lumen balloons for use as or in conjunction with balloon dilation catheters, and methods for making such balloons, are disclosed.
• 5,624,392: Heat Transfer Catheters and Method of Making and Using Same
  Heat transfer catheter apparatus and methods of making and using same are disclosed where fluid connection means is provided between the distal portions of two adjacent, thin-walled, high strength fluid lumens to define a closed loop fluid circulation system capable of controlled delivery of thermal energy to or withdrawal of thermal energy from remote internal body locations.
• 5,902,268: Heat Transfer Catheter Apparatus and Method of Making and Using Same
  Heat transfer catheter apparatus and methods of making and using same are disclosed where fluid connection means is provided between the distal portions of two adjacent, thin-walled, high strength fluid lumens to define a closed loop fluid circulation system capable of controlled delivery of thermal energy to or withdrawal of thermal energy from remote internal body locations.
• 6,440,158B1: Heat Transfer Catheter Apparatus and Method of Making and Using Same
  Heat transfer catheter apparatus and methods of making and using same are disclosed wherein a fluid connection is provided between the distal portions of two adjacent, thin-walled, high strength fluid lumens to define a closed loop fluid circulation system capable of controlled delivery of thermal energy to or withdrawal of thermal energy from remote internal body locations.
• 6,623,516: Method for Changing the Temperature of a Selected Body Region
  Heat transfer catheter apparatus and methods of making and using same are disclosed wherein a fluid connection is provided between the distal portions of two adjacent, thin-walled, high strength fluid lumens to define a closed loop fluid circulation system capable of controlled delivery of thermal energy to or withdrawal of thermal energy from remote internal body locations.
• 6,905,510: Heat Transfer Catheters and Methods of Making and Using the Same
  Heat transfer catheter apparatus and methods of making and using same are disclosed wherein a fluid connection is provided between the distal portions of two adjacent, thin-walled, high strength fluid lumens to define a closed loop fluid circulation system capable of controlled delivery of thermal energy to or withdrawal of thermal energy from remote internal body locations.
• 6,966,889B2: Multi-Lumen Catheters and Methods for Using Same
  Very thin-walled multi-lumen catheters wherein each of at least three of the catheter lumens shares a common, integrally-formed wall portion with at least one adjacent catheter lumen are disclosed together with methods for using such catheters in medical treatment applications.

Additional Intellectual Property Rights owned by Advanced Polymers

In May of 2001, Advanced Polymers acquired the exclusive right, title and interest in and to IP previously owned by E-Med (Cor-Trak). These patents are available for license from Advanced Polymers.

• 5,282,785: Drug Delivery Apparatus and Method
  A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is transported across a drug transport wall of the device for direct contact with the passageway all or body tissue. A further aspect of the present invention involves treating a dilated vessel in the area of a stenotic lesion with a fixative or other drug to render the vessel biologically inert and to form a biological stent or prevent restenosis using specifically selected drugs. A still further aspect of the present invention involves treating a tumor or local or regional tissue mass with antitumor sensitizing agents, biological modifiers, antibiotics or other types of drugs by delivery of the drug to the tumor or tissue area directly or through the passageway wall.
• 5,286,254: Drug Delivery Apparatus and Method
  A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is transported across a drug transport wall of the device for direct contact with the passageway all or body tissue. A further aspect of the present invention involves treating a dilated vessel in the area of a stenotic lesion with a fixative or other drug to render the vessel biologically inert and to form a biological stent or prevent restenosis using specifically selected drugs. A still further aspect of the present invention involves treating a tumor or local or regional tissue mass with antitumor sensitizing agents, biological modifiers, antibiotics or other types of drugs by delivery of the drug to the tumor or tissue area directly or through the passageway wall.
• 5,458,568: Porous Balloon for Selective Dilatation and Drug Delivery
  A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively wetting a membrane within the device, making the membrane permeable and allowing transport of a drug across the membrane and into the passageway wall or body tissue.
• 5,498,238: Simultaneous Angioplasty and Phoretic Drug Delivery
  A method of simultaneous angioplasty and drug delivery to a localized portion of coronary or peripheral arteries or any other type of body passage that has a stricture. The invention contemplates positioning a drug delivery device in a body passageway and then selectively introducing a selected drug so that the device is expanded in order to dilate the passage and then simultaneously causing the drug to be transported across a drug transport wall of the device for direct contact with the passageway wall. A more specific aspect of the present invention involves treating a dilated vessel in the area of a stenotic lesion with a fixative or other drug to render the vessel biologically inert and to form a biological stent or prevent restenosis using specifically selected drugs.
• 5,499,971: Method for Iontophoretically Delivering Drug Adjacent to a Heart
  A drug delivery apparatus and method for iontophoretically delivering a drug locally to internal body tissue. The iontophoretic delivery apparatus and method include a current source producing a net flow of current in a desired direction with high frequency waveforms which enhance delivery and minimize side effects typically associated with iontophoresis.
• 5,569,198: Microporous Catheter
  An apparatus for delivering an agent to a treatment area. The apparatus includes a catheter that has a distal portion and a proximal portion. The catheter defines a lumen. A pressure regulator is in fluid communication with the lumen. A selectively inflatable member is also in fluid communication with the lumen, and is formed from a membrane. The membrane has first and second portions. The first portion defines pores sized from about 0.05 to about 1 and has a pore density from about 106 pores/cm2 to about 109 pores/cm2. the flux rate is from about 0.001 ml/(min*cm2*atm) to about 0.4 ml/(min*cm2*atm). The second portion is substantially impermeable.
• 5,628,730: Phoretic Balloon Catheter with Hydrogel Coating
  A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is transported across a drug transport wall of the device for direct contact with the passageway wall or body tissue. A further aspect of the present invention involves treating a dilated vessel in the area of a stenotic lesion with a fixative or other drug to render the vessel biologically inert and to form a biological stent or prevent restenosis using specifically selected drugs. A still further aspect of the present invention involves treating a tumor or local or regional tissue mass with antitumor sensitizing agents, biological modifiers, antibiotics or other types of drugs by delivery of the drug to the tumor or tissue area directly or through the passageway wall.
• 5,634,899: Simultaneous Cardiac Pacing and Local Drug Delivery Method
  An apparatus and method for delivering a drug selectively and locally to internal body tissue with a catheter using electric current/voltage controlled in conjunction with active pacing of cardiac activity.
• 5,800,392: Microporous Catheter
  An apparatus for delivering an agent to a treatment area. The apparatus includes a catheter that has a distal portion and a proximal portion. The catheter defines a lumen. A pressure regulator is in fluid communication with the lumen. A selectively inflatable member is also in fluid communication with the lumen, and is formed from a membrane. The membrane has first and second portions. The first portion defines pores sized from about 0.05 to about 1 and has a pore density from about 106 pores/cm2 to about 109 pores/cm2. the flux rate is from about 0.001 ml/(min*cm2*atm) to about 0.4 ml/(min*cm2*atm). The second portion is substantially impermeable.
• 5,807,306: Polymer Matrix Drug Delivery Apparatus
  A drug delivery apparatus and method for delivering a drug locally to internal body tissue using a catheter device including a polymer matrix containing a drug. The drug is actively transported from the polymer matrix to the internal body tissue using iontophoresis or phonophoresis. In addition, the polymer matrix can be expanded to promote intimate contact with the walls of a passageway or vessel.
• 5,865,787: Simultaneous Cardiac Pacing and Local Drug Delivery
  An apparatus and method for delivering a drug selectively and locally to internal body tissue with a catheter using electric current/voltage controlled in conjunction with active pacing of cardiac activity.